The Long Term Efficacy of High Frequency Repetitive Transcranial Magnetic Stimulation on Postural Stability in Parkinsonian Patients.

Trial ID: NCT05198076

Interventional - Phase Unknown - Recruiting

Postural instability is one of the cardinal signs in Parkinson's disease (PD). It represents one of the most disabling symptoms in the advanced stages of the disease. It is associated with frequent falls and loss of independence. The aim of the current study is to assess the long term efficacy of high frequency repetitive transcranial magnetic stimulation (rTMS) on improving postural instability in PD patients.

Conditions

• Parkinson Disease

Interventions

• High Frequency Repetitive Transcranial Magnetic Stimulation

Eligibility

Inclusion criteria

• All included patients should fulfill the U.K Parkinson's Disease Brain Bank Criteria for idiopathic PD.
• Patients with mild to moderate disease severity according to UPRS and Modified Hoehn and Yahr staging
• Duration of illness from two to five years were included.
• All included patients should be medically and psychologically stable and of adequate cardiac function.
• All included patients should haven't receive any rTMS sessions before.
• Signed consent form should be taken from all included patients.

Exclusion criteria

• Patients with implanted devices, serious medical illness or history of seizures were excluded.
• Patients with severe freezing phenomenon or severe tremors were excluded

Sponsor

Cairo University

Source: ClinicalTrials.gov

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