Neuro-Oncology Anywhere 242: Pilot Study Evaluating Telehealth and In-Person Assessments in Patients With Glioma Receiving Oral Chemotherapy

Trial ID: NCT06625047

Interventional - Phase 4 - Completed

This phase IV trial compares patient satisfaction with telehealth versus in-person neuro-oncology assessments among glioma patients receiving oral chemotherapy. Gliomas are the most common primary central nervous system cancer and are associated with a high symptom burden, such as drowsiness, fatigue, memory difficulty, and difficulty communicating. Care at a high volume center is associated with an overall survival benefit, however, many patients may have physical or financial difficulties preventing access to these centers. Telehealth visits use computers, cameras, videoconferencing, the internet, satellite, and wireless communications to deliver healthcare, while in-person visits require the interaction to take place in the physical presence of someone else. Telehealth neuro-oncology assessments may be preferable compared to in-person assessments in glioma patients receiving oral chemotherapy.

Conditions

• Astrocytoma, IDH-Mutant
• Glioblastoma
• Glioma
• Oligodendroglioma, IDH-Mutant and 1p/19q-Codeleted

Interventions

• Assessment
• Questionnaire Administration
• Telemedicine Visit
• Temozolomide

Eligibility

Inclusion criteria

• Age ≥ 18 years
• Diagnosis of glioma requiring adjuvant chemotherapy. Patients with glioblastoma (GBM); astrocytoma, IDH-mutant; oligodendroglioma IDH-mutant, 1p/19q codeleted are eligible
• Patients eligible to receive temozolomide as standard of care adjuvant therapy
• Eastern Cooperative Oncology Group (ECOG) performance status of 0, 1, or 2, AND Karnofsky performance status (KPS) of ≥ 60
• Expected survival ≥ 6 months in the opinion of treatment team
• Willing and able to adhere with the protocol for the duration of the study including undergoing treatment, and attending scheduled visits, and examinations
• Participants who do not have devices that will permit telehealth visits will be provided such tablet devices to facilitate appointments for the duration of the study
• Participants who do not have financial resources to travel for in-person visits will be provided assistance for cost of travel
• Ability to complete patient experience surveys by the participant with or without assistance from their caregiver

Exclusion criteria

• Uncontrolled and/or intercurrent illness or other condition which limits safety of or compliance with study proceedings
• Pregnant or nursing, imprisoned, or lacking capacity for understanding
• Unable to swallow tablets or at risk for impaired absorption of oral medication
• Known hypersensitivity or allergy to temozolomide

Sponsor

Mayo Clinic

Source: ClinicalTrials.gov

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