Efficacy and Safety of Transcranial dIrect Current stiMulation (tDCS) on Cerebellar Symptoms in Multiple System Atrophy-Cerebellar Variant (MSA-C) (STIM-MSA)

Trial ID: NCT06821256

Interventional - Phase Unknown - Recruiting

This is a double-blind, randomized, sham-controlled clinical trial that aim to verify the safety and the efficacy of anodal transcranial direct current stimulation (tDCS) cerebellar symptoms in Multiple System Atrophy type C (MSA).

Conditions

• Multiple System Atrophy - Cerebellar Subtype (MSA-C)

Interventions

• Anodal transcranial direct current stimulation (a-tDCS)
• Sham stimulation

Eligibility

Inclusion criteria

• Multiple system atrophy cerebellar variant according with the Movemente Disorder Society criteria (Wenning et al 2022)
• Ability to walk either indipendently or with a minimum support

Exclusion criteria

• Presence of electrical stimulators (for example, pacemaker, Deep Brain Stimulation, DBS)
• Difficult in understanding Italian language
• Presence of severe sensory deficits (for example, visual or hearing impairments)
• History of drug abuse
• History of severe psychiatric disorders
• History of transient ischemic attacks
• Cortical or sub-cortical vascular lesions
• Seizures or severe heart problems and previous neurosurgical operations
• Pregnancy

Sponsor

University of Salerno

Source: ClinicalTrials.gov

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